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The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Systematic Review PMC

does spironolactone cause hair loss

Your doctor will likely perform this test on a regular basis while you take Aldactone. However, if you develop hyperkalemia (a high level of potassium in your blood), your doctor will likely lower the dosage to 25 mg, every other day. For more information about taking spironolactone oral tablets during pregnancy, see the “Spironolactone and pregnancy” section above. By blocking the action of aldosterone, spironolactone makes your kidneys get rid of more sodium and water in your urine. It also makes your kidneys keep more potassium in your blood.

Aldactone (spironolactone)

Your doctor may monitor you closely if you take these drugs together. Spironolactone oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works.

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Breastfeeding

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does spironolactone cause hair loss

Aldactone vs. Entresto

Aldactone may be used for a short time to manage your symptoms before surgery for primary hyperaldosteronism. Aldactone is approved to treat primary hyperaldosteronism in certain situations. For this purpose, your doctor will likely have you start with an Aldactone dosage of 100 mg per day. They may have you take this in one single dose or divide it into two or three doses. In addition to the uses listed above, Aldactone may be prescribed off-label for other purposes. Off-label drug use is when a drug that’s approved for one or more use(s) is prescribed for a different one that’s not approved.

When to See a Medical Professional

Sharing this information can help you avoid potential interactions. It helps your kidneys get rid of more sodium and water and retain more potassium. This lowers your blood pressure and increases your potassium level. Spironolactone oral tablets are an effective blood pressure-lowering medication.

So, while some people taking weight loss drugs have reported hair loss, that loss could be due to malnutrition. Chemotherapy drugs may be the best-known cause of drug-induced alopecia. However, hair loss is a possible side effect of many different medications.

Spironolactone for high blood pressure

This was a secondary effect that was discovered in later studies of the medication. Spironolactone is an oral form of medication that was initially developed to treat mild blood pressure irregularities and water retention. “Structurally, its backbone is a basic steroidal nucleus with four rings. The primary metabolite of spironolactone is canrenone, which is an active metabolite that is also an antagonist of aldosterone, and thus promotes diuresis,” Gonzalez explains.

Weight loss/gain

You can also ask your pharmacist for information about how to dispose of your medication. How long a medication remains good to use can depend on many factors, including how and where you store the medication. Spironolactone oral tablets are meant to be swallowed whole. For more information about the conditions listed below, see the “Spironolactone uses” section above.

Call your doctor right away if you have serious side effects. Call 911 or your local emergency number if your symptoms feel life threatening or if you think you’re having a medical emergency. Female pattern hair loss, also known as female androgenetic alopecia, is a common form of hair loss in women that affects up to 50% of women over the age of 50 [1]. The overall rate of improved hair loss was 56.60%, with a higher rate of improvement (65.80%) observed in the combined therapy group compared to the monotherapy group (43.21%).

If you’re having surgery for this condition, you’ll take spironolactone for a short time before your surgery. Doing so helps to lower your blood pressure and increase your potassium level before the surgery. The usual dosage of spironolactone oral tablets for this use is 100 mg to 400 mg per day. Spironolactone may be prescribed for androgenic alopecia in females. With this condition, you have hair loss that’s caused by too much of the hormone testosterone in your body. Most of the common side effects of spironolactone are temporary and will fade when the drug is discontinued.

does spironolactone cause hair loss

Also the acne is just as bad, the Spiro hasn’t seemed to help it at all. Some people have serious side effects after taking spironolactone. If you get unusual muscle cramps that are not from exercise or physical work, talk to your doctor. According to the drug’s manufacturer, it isn’t known whether Aldactone is safe to use while breastfeeding. However, the National Institutes of Health (NIH) says that spironolactone, the active drug in Aldactone, appears to be safe to use while breastfeeding. Talk with your doctor or pharmacist if you have questions about your medication.

There are also several ongoing trials whose objective is to validate the effects of spironolactone on AGA, but whose results have not been published yet, not detailed or incomplete. Spironolactone is a prescription medication typically used to treat various health concerns, such as high blood pressure, low potassium levels, and heart or kidney disease. However, it can also be used to promote hair growth in women suffering from androgenetic alopecia, also known as female pattern hair loss. Five included studies11–15 reported the use of oral spironolactone in 295 female patients. Most participants received the treatment for up to one year or more, yet the minimum duration of oral spironolactone use in these included studies was 24 weeks.

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Many different factors contribute to this condition, including certain medications. Doctors refer to alopecia that occurs as a side effect of medication as drug-induced alopecia. I recently began taking Spironolactone 50mg two wks ago for my acne. It started shedding a lot more & a lot came out in the shower. I really didn’t think it was the medicine though I did read starting a BP medication (or just a new medication in general) could cause hair loss.

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